Hydroxyethyl Theophylline

Hydroxyethyl Theophylline is a bronchodilator that belongs to the xanthine class of drugs. It is used primarily to treat respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD).

Indications

-Asthma -Chronic obstructive pulmonary disease (COPD) -Bronchospasm -Emphysema -Chronic bronchitis

Dosage

The dosage of Hydroxyethyl Theophylline varies based on the patient's age, weight, and severity of the condition. It is essential to follow the prescribing physician's instructions or the guidelines on the prescription label. Regular monitoring of blood levels is recommended to avoid toxicity.

Contra-Indications

-Hypersensitivity to theophylline or any component of the formulation -Active peptic ulcer disease -Seizure disorders not adequately controlled by medication -Cardiac arrhythmias

Special Precautions

-Monitor serum theophylline levels regularly to avoid toxicity. -Use with caution in patients with heart disease, hypertension, liver impairment, or thyroid dysfunction. -Caution in elderly patients due to increased risk of side effects. -Avoid abrupt discontinuation to prevent withdrawal symptoms. -Adjust dose in patients with renal or hepatic impairment.

Side Effects

-Nausea and vomiting -Diarrhea -Headache -Insomnia -Irritability -Increased heart rate (tachycardia) -Seizures (in case of overdose)

Drug Interactions

-Increased effects with cimetidine, erythromycin, fluoroquinolones, and oral contraceptives. -Decreased effects with phenytoin, carbamazepine, and barbiturates. -Use with caution when combined with other xanthine drugs, beta-blockers, or alcohol.