IFOSFAMIDE

It is a newer congener of cyclophosphamide.

Indications

Bronchogenic carcinoma, testicular carcinoma, malignant lymphoma, soft tissue sarcoma, osteo sarcoma.

Contra-Indications

Acute Urinary tract infection. Pregnancy.

Special Precautions

Chloramphenicol retards the metabolism of cyclophosphamide. Elderly, debilitated, diabetes. Discontinue if W.B.C. Count is less than 3000. Cardiac, hepatic or renal disease.

Side Effects

Alopecia, gonadal suppression, cardiotoxicity. ulmonary fibrosis.