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Ketotifen

Ketotifen

It posseses marked anti-anaphylactic properties and is effective in preventing asthmatic attacks but will not abort established attacks of asthma.

Indications

Prophylactic treatment of bronchial asthma. Symptomatic treatment of allergic conditions including rhinitis and conjunctivitis.


Dosage

1 mg twice daily with food.Max. 2 mg twice daily. Children 6 months -2 yrs. : 0.5 mg twice daily with food. 2 yrs. onwards : 1 mg twice daily with food.


Contra-Indications

A reversible fall in the thrombocyte count in patients receiving ketotifen concomitantly with oral anti-diabetic agents has been observed in a few patients.


Special Precautions

Existing treatment (especially systemic corticosteroids & ACTH) should be continued for a minimum two weeks after starting ketotifen. Not to operate machinery or vehicles & to avoid alcoholic drinks. It may potentiate the effects of sedatives, hypnotics, anti-histamines and alcohol. Paediatrics: Safe. Pregnancy: Should not be used. Lactation: Safe. Elderly: Safe.


Side Effects

Drowsiness, dry mouth, dizziness.


Drug Interactions

Potentiate effects of sedatives hypnotics antihistamines and alcohol. Reversible fall in platelet count with concomitant use of oral antidiabetics, others may reverse chloroquine resistance and potentiat action of sulphadoxine in acute malaria.


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