L-thyroxine

L-thyroxine, also known as levothyroxine, is a synthetic form of the thyroid hormone thyroxine (T4). It is used to treat hypothyroidism, a condition where the thyroid gland does not produce enough thyroid hormone. L-thyroxine helps restore normal metabolism and energy levels by replacing the deficient hormone.

Indications

-Hypothyroidism -Goiter -Thyroid cancer (as part of the treatment)

Dosage

The dosage of L-thyroxine varies depending on the patient's age, weight, medical condition, and response to treatment. It is usually taken orally once daily on an empty stomach, preferably 30 minutes to an hour before breakfast. Dosage adjustments are based on regular monitoring of thyroid function tests.

Contra-Indications

-Untreated adrenal insufficiency -Thyrotoxicosis -Hypersensitivity to L-thyroxine or any of its components

Special Precautions

Monitor thyroid function regularly -Use with caution in patients with cardiovascular disease, diabetes, or osteoporosis -Adjust dosage carefully in elderly patients -Inform healthcare provider of all medical conditions and medications

Side Effects

-Palpitations -Increased heart rate -Nervousness -Insomnia -Weight loss -Heat intolerance -Menstrual irregularities

Drug Interactions

-Antacids, calcium supplements, and iron supplements can reduce absorption of L-thyroxine -Certain medications such as anticoagulants, beta-blockers, and antidepressants may require dosage adjustments -Insulin or oral hypoglycemic drugs may need to be adjusted due to changes in thyroid hormone levels