Letrozole
It is a non-steroidal aromatase inhibitor and is considered alternative to tamoxifen for the treatment of advanced, post menopausal breast cancer.Advanced breast cancer in post-menopausal women, pre-operative treatment in post-menopausal women with localised hormone-receptor-positive breast cancer (to allow subsequent breast conserving surgery).
Severe hepatic impairment, premenopausal women.
Severe renal impairment.
Diarrhoea, abdominal pain, anorexia or weight gain, dyspnoea, chest pain, dizziness, rash, pruritus, vomiting, dyspepsia, constipation, hot flushes, nausea.