Look for Drugs and Conditions

Letrozole

Letrozole

It is a non-steroidal aromatase inhibitor and is considered alternative to tamoxifen for the treatment of advanced, post menopausal breast cancer.

Indications

Advanced breast cancer in post-menopausal women, pre-operative treatment in post-menopausal women with localised hormone-receptor-positive breast cancer (to allow subsequent breast conserving surgery).


Contra-Indications

Severe hepatic impairment, premenopausal women.


Special Precautions

Severe renal impairment.


Side Effects

Diarrhoea, abdominal pain, anorexia or weight gain, dyspnoea, chest pain, dizziness, rash, pruritus, vomiting, dyspepsia, constipation, hot flushes, nausea.


Ad 5