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Levalbuterol

Levalbuterol

Levalbuterol is a short-acting beta-2 adrenergic agonist (SABA) bronchodilator used primarily to treat or prevent bronchospasm in individuals with reversible obstructive airway conditions, such as asthma. It works by relaxing and opening the airways in the lungs, making breathing easier.

Indications

Treatment or prevention of bronchospasm in individuals with reversible obstructive airway diseases, such as asthma.


Dosage

-Adults and children 4 years and older: Dosage varies depending on the form of levalbuterol (e.g., inhalation solution or metered-dose inhaler) and the severity of the condition. Follow your healthcare provider's instructions for the correct dosage and frequency. -Inhalation solution: Typically administered via nebulizer. Common dosages range from 0.31 mg to 1.25 mg three times a day. -Metered-dose inhaler: Usually 2 puffs (90 mcg each) every 4 to 6 hours as needed for symptoms.


Contra-Indications

-Known hypersensitivity to levalbuterol or any component of the formulation. -Hypersensitivity to other sympathomimetic amines.


Special Precautions

-Cardiovascular effects: Levalbuterol may cause an increase in heart rate and blood pressure; use with caution in patients with cardiovascular conditions. -Hyperthyroidism: Use cautiously in individuals with thyroid issues. -Diabetes: Blood glucose levels may be affected; monitor blood sugar in diabetic patients. -Paradoxical bronchospasm: Rarely, levalbuterol may worsen bronchospasm; discontinue use and seek medical attention if this occurs. -Use in children: The safety and efficacy in children younger than 4 years of age have not been established.


Side Effects

-Common side effects include headache, dizziness, nervousness, shakiness, palpitations, and muscle cramps. -Other possible side effects include throat irritation, dry mouth, and chest pain.


Drug Interactions

-Beta-blockers: May decrease the effectiveness of levalbuterol and cause bronchospasm. -Diuretics: May increase the risk of hypokalemia when used with levalbuterol. -MAO inhibitors and tricyclic antidepressants: May intensify the cardiovascular effects of levalbuterol.


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