Losartan Potassium with Amlodipine

Losartan Potassium with Amlodipine is a combination medication used to manage hypertension (high blood pressure). Losartan is an angiotensin II receptor blocker (ARB), and Amlodipine is a calcium channel blocker. Together, they work to relax blood vessels, reducing blood pressure.

Indications

-Hypertension: Used to treat essential hypertension (high blood pressure) in patients where monotherapy is insufficient.

Dosage

Dosage varies depending on the specific needs of the patient and the severity of hypertension. The combination is usually administered orally, once daily.

Contra-Indications

-Pregnancy: Avoid use during pregnancy, especially in the second and third trimesters. -Hypersensitivity: Patients with known hypersensitivity to losartan, amlodipine, or any component of the combination.

Special Precautions

-Renal Impairment: Caution in patients with renal impairment; monitor renal function regularly. -Hepatic Impairment: Adjustments in dosage may be necessary for patients with liver dysfunction.

Side Effects

Common side effects may include dizziness, flushing, peripheral edema, and headache. Serious side effects are rare but may include hypotension, hyperkalemia, or allergic reactions.

Drug Interactions

-Lithium: Increased risk of lithium toxicity when used concurrently. -Potassium-Sparing Diuretics: Increased risk of hyperkalemia when used with other agents that raise potassium levels.