Losartan potassium with Perindopril Erbumine

Losartan potassium and perindopril erbumine are medications used to treat hypertension (high blood pressure). Losartan is an angiotensin II receptor blocker (ARB), and perindopril is an angiotensin-converting enzyme (ACE) inhibitor. The combination of these two drugs helps to relax blood vessels, reducing blood pressure and improving overall cardiovascular health.

Indications

Hypertension (high blood pressure) when monotherapy is not sufficient.

Dosage

The dosage may vary depending on the patient's individual health condition. It is essential to follow the prescribed dosage provided by the healthcare provider.

Contra-Indications

These medications are contraindicated in patients with a history of hypersensitivity to any component of the product, patients with a history of angioedema related to previous ACE inhibitor therapy, and during pregnancy.

Special Precautions

-Renal impairment: Caution is advised in patients with renal impairment. -Hyperkalemia: Monitoring of potassium levels is recommended, especially in patients with renal impairment or diabetes. -Hypotension: Caution is required in patients at risk of excessive hypotension, such as those with volume depletion.

Side Effects

Common side effects may include dizziness, hypotension, hyperkalemia, and changes in renal function. It's important to report any unusual or severe side effects to a healthcare professional.

Drug Interactions

-Potassium-sparing diuretics and potassium supplements may increase the risk of hyperkalemia. -Non-steroidal anti-inflammatory drugs (NSAIDs) may reduce the antihypertensive effects of the medication. -Dual blockade of the renin-angiotensin-aldosterone system may increase the risk of hypotension, hyperkalemia, and renal impairment.