Methyl Hydroxy Benzoate

Methyl Hydroxy Benzoate, also known as methylparaben, is a preservative commonly used in pharmaceuticals, cosmetics, and food products. It belongs to the class of parabens and is primarily employed to inhibit microbial growth and extend the shelf life of various formulations.

Indications

-Pharmaceuticals: Used as a preservative in liquid oral preparations, topical formulations, and injectables. -Cosmetics: Found in creams, lotions, and other personal care products to prevent microbial contamination. -Food Industry: Occasionally used to preserve certain food products.

Dosage

The dosage of Methyl Hydroxy Benzoate varies depending on the specific formulation and intended use. It is typically used in concentrations ranging from 0.1% to 0.5% in cosmetic and pharmaceutical products, adhering to regulatory guidelines for safe use.

Contra-Indications

-Hypersensitivity: Individuals with known hypersensitivity to parabens should avoid products containing Methyl Hydroxy Benzoate. -Avoidance in Certain Conditions: Caution is advised in patients with compromised skin barrier function or specific dermatological conditions.

Special Precautions

-Pregnancy and Lactation: Safety during pregnancy and breastfeeding is not well established; cautious use is recommended. -Pediatric Use: Use in infants and young children should be carefully monitored due to potential increased absorption through the skin.

Side Effects

-Skin Irritation: Mild to moderate skin reactions such as redness or itching can occur in sensitive individuals. -Allergic Reactions: Rare cases of allergic dermatitis or contact urticaria have been reported.

Drug Interactions

Methyl Hydroxy Benzoate is not known to interact significantly with other medications. However, caution should be exercised when combining with topical medications or products containing other preservatives to avoid potential additive effects.