METHYLERGOMETRINE
Methylergometrine is a medication belonging to the ergot alkaloid group, primarily used to prevent or treat excessive bleeding after childbirth (postpartum hemorrhage). It works by causing contractions of the smooth muscle of the uterus, which helps to control bleeding.-Prevention and treatment of postpartum hemorrhage (excessive bleeding after childbirth). -Management of uterine atony (lack of uterine muscle tone) after delivery.
The dosage of methylergometrine typically varies depending on the clinical situation and should be administered under medical supervision: -For prevention of postpartum hemorrhage: Usually administered shortly after delivery, often as a single dose. -For treatment of postpartum hemorrhage: Typically given either intramuscularly or intravenously.
Methylergometrine is contraindicated in certain conditions: -Hypertension (high blood pressure). -Pre-eclampsia or eclampsia. -Coronary artery disease. -Peripheral vascular disease. -Sepsis.
Special care should be taken when administering methylergometrine in the following situations: -Patients with impaired liver or kidney function. -History of cardiovascular disease. -Use in conjunction with other uterotonic agents.
Common side effects may include: -Nausea and vomiting. -Headache. -Dizziness. -Hypertension (elevated blood pressure).
Methylergometrine may interact with: -Beta-blockers (can enhance hypertensive effects). -Ergot alkaloids (increased risk of ergotism). -Certain antibiotics and antifungal medications (may alter metabolism).
