Nebivolol with Indapamide

Nebivolol is a beta-blocker that works by affecting the heart and circulation. It is used to treat hypertension (high blood pressure). Indapamide is a diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention. This combination medication is prescribed to manage high blood pressure effectively.

Indications

-Hypertension (high blood pressure).

Dosage

Dosage may vary based on individual patient factors. Typically, a common starting dose may be nebivolol 5 mg/indapamide 1.25 mg once daily. The dosage can be adjusted by a healthcare professional according to the patient's response.

Contra-Indications

This combination is contraindicated in patients with: -Hypersensitivity to nebivolol, indapamide, or any component of the formulation. -Severe liver impairment. -Severe renal impairment (glomerular filtration rate <30 mL/min).

Special Precautions

-Caution should be exercised in patients with asthma, chronic obstructive pulmonary disease (COPD), diabetes, and peripheral vascular disease. -Patients with a history of heart failure should be monitored closely. -Avoid abrupt withdrawal of the medication, particularly in patients with coronary artery disease.

Side Effects

Common side effects may include dizziness, fatigue, headache, and fluid retention. Notify your healthcare provider if you experience any unusual or severe side effects.

Drug Interactions

-Concurrent use with other antihypertensive agents may enhance the blood pressure-lowering effects. -Avoid concurrent use with monoamine oxidase inhibitors (MAOIs). -Caution should be exercised when used concomitantly with certain medications, such as insulin or oral antidiabetic agents.