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It is water soluble bactericidal aminoglycoside.


Bacteraemia, Septicaemia, Respiratory tract, Kidney and genitourinary tract, Skin, Soft tissue, bone, joints, burns, wounds, pre-operative, intra-abdominal and gastro-intestinal tract infections.Infections caused by micro-organisms resistant to Kanamycin, gentamicin, tobramycin, sisomicin and amikacin.


Adults : 4 to 6 mg/kg/day in 1-3 equal divided doses. Paediatric Patients : One week or less 3.0 mg/kg every 12 hrs. Neonates and infants : 2.5 to 3.0 mg/kg every 8 hrs. Children : 2.0 to 2.5 mg/kg every 8 hrs.



Special Precautions

Neurotoxicity, Nephrotoxicity. Paediatrics & Elderly: Use with caution. Pregnancy & Lactation: Use with caution

Side Effects

Ototoxicity, pain at injection site, headache, visual disturbances, disorientation, tachycardia, hypotension.

Drug Interactions

Enhances toxicity of frusemide and ethacrynic acid. Potentiates neurotoxicity/nephrotoxicity by other aminoglycosides, cephaloridine, polymixin B, cisplatin and vancomycin. Potentiates neuromuscular blocking agents. Incompatible with beta-lactum antibiotics.

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