Nicinamide

Nicinamide, also known as niacinamide, is a form of vitamin B3 (niacin). It is an essential nutrient that supports the body in converting food into energy and maintaining healthy cells. Unlike niacin, nicinamide does not cause flushing. It is commonly used in dietary supplements and skin care products due to its numerous health benefits.

Indications

-Prevention and treatment of niacin deficiency (pellagra) -Management of acne and skin inflammation -Support in improving skin barrier function and hydration -Potential aid in reducing hyperpigmentation and fine lines -Supportive treatment for certain skin conditions like rosacea

Dosage

-For Pellagra (niacin deficiency): 300 mg per day in divided doses -For Acne and Skin Conditions: Topical application of 2-5% nicinamide gel or cream, as directed by a healthcare provider -Dietary Supplement: 20-35 mg daily as part of a multivitamin

Contra-Indications

-Hypersensitivity to nicinamide or any component of the formulation -Severe liver disease -Peptic ulcer disease -Arterial bleeding

Special Precautions

-Use cautiously in patients with liver disease or diabetes -Regular monitoring of liver function tests may be required -Consult a healthcare provider before use during pregnancy and breastfeeding

Side Effects

-Nausea -Diarrhea -Headache -Dizziness -Flushing (less common than with niacin) -Itching or rash (rare)

Drug Interactions

-Alcohol: May increase the risk of liver damage -Statins: Potential for increased risk of myopathy or liver damage -Antidiabetic drugs: May affect blood sugar levels