Nicotinic Acid

Nicotinic Acid, also known as Niacin or Vitamin B3, is a water-soluble vitamin essential for various bodily functions, including lipid metabolism and cardiovascular health. It helps in reducing cholesterol levels and improving overall heart health.

Indications

-Hyperlipidemia (high cholesterol levels) -Pellagra (niacin deficiency) -Prevention and treatment of atherosclerosis -Improving blood circulation

Dosage

-Adults: Typically 500 mg to 2,000 mg per day, divided into doses. Adjustments may be made based on individual response and tolerance. -Children: Dosage should be determined by a healthcare provider based on specific needs and conditions.

Contra-Indications

-Hypersensitivity to nicotinic acid or any of its components -Severe liver dysfunction -Peptic ulcer disease -Active bleeding disorders

Special Precautions

-Use with caution in individuals with liver disease, diabetes, or gout. -Monitor liver function tests regularly during long-term use. -May cause flushing; start with a lower dose and gradually increase to minimize this effect.

Side Effects

-Flushing of the skin -Itching -Nausea and vomiting -Abdominal pain -Headache -Liver toxicity (with high doses) -Hypoglycemia (low blood sugar)

Drug Interactions

-May enhance the effects of antihypertensive medications. -May interact with anticoagulants, increasing the risk of bleeding. -Caution when used with statins, as it may increase the risk of muscle-related side effects.