Nimesulide, Paracetamol, Phenylephrine, Caffeine, Cetirizine, Tulsi Extract, Beta Cyclodextrin

This medication is a combination of several active ingredients, including Nimesulide (a nonsteroidal anti-inflammatory drug), Paracetamol (acetaminophen), Phenylephrine (a decongestant), Caffeine (a stimulant), Cetirizine (an antihistamine), Tulsi Extract (Holy Basil), and Beta Cyclodextrin (a solubilizing agent). This combination is formulated to provide relief from symptoms associated with cold, flu, allergies, and inflammation.

Indications

-Relief of pain and inflammation associated with colds and flu -Fever reduction -Nasal congestion relief -Allergy symptom relief -Mild to moderate pain relief -Enhancing alertness and combating fatigue

Dosage

Dosage may vary depending on the patient's age, weight, and medical condition. It is essential to follow the instructions provided by the healthcare provider or the medication label. Typically, the dosage for adults may be one to two tablets every 4-6 hours, not exceeding a maximum daily dosage. Children's dosage should be determined based on weight and age, following pediatrician recommendations.

Contra-Indications

-Hypersensitivity to any of the active ingredients -Severe renal impairment -Severe hepatic impairment -Pregnancy (especially in the first and third trimesters) -Breastfeeding -History of gastrointestinal bleeding or perforation -History of cardiovascular diseases -Concurrent use with monoamine oxidase inhibitors (MAOIs)

Special Precautions

-Use with caution in patients with a history of asthma or other respiratory conditions -Avoid excessive caffeine consumption from other sources while taking this medication -Elderly patients may be more susceptible to adverse effects and should use with caution -Avoid alcohol consumption while taking this medication -Monitor renal and hepatic function regularly during prolonged use

Side Effects

-Nausea and vomiting -Headache -Dizziness -Insomnia -Palpitations -Increased blood pressure -Allergic reactions (rash, itching, swelling) -Gastric irritation or ulceration -Renal impairment

Drug Interactions

-Increased risk of gastrointestinal bleeding when combined with other NSAIDs or corticosteroids -Enhanced sedative effects when combined with alcohol or other central nervous system depressants -Potential for increased blood pressure when combined with sympathomimetic agents or monoamine oxidase inhibitors (MAOIs) -Possible decrease in effectiveness of antihypertensive medications