Nitazoxanide
It is a synthetic antiprotozoal drug; 2-acetyloxy-N-(5-nitro-2-thiazolyl) benzamide. Nitazoxanide exhibits antiprotozoal activity by interfering with PFOR (Pyruvate:ferredoxin oxidoreductase) enzyme dependent electron transport reaction that is essential for anaerobic energy metabolism.Diarrhoea & Dysentery caused by Giardia lamblia & Cryptosporitidium parvum & Entamoeba histolytica. Infections caused by Helminthes e.g. Trichuris trichiura, Ascaris lumbricoides, Hymenolepiasis nana & Enterobius vermicularis.
1-3 years : Nitazoxanide 100mg (5ml) BID for 3 days. 4-11 years : Nitazoxanide 200mg (10ml) BID for 3 days. 12 years & above : Nitazoxanide 500mg BID for 3 days. Pediatric dosage : 7.5mg/kg BID for 3 days.
Prior Hypersensitivity to Nitazoxanide.
Nitazoxanide must be administered with caution in patients of hepatic, renal & biliary disease. Pregnancy: Category B.
Abdominal pain, Headache & Nausea.
Brand Name | Manufactured by |
---|---|
NITACURE | ALEMBIC LTD. |
NITOLEY | Zodley Pharmaceuticals Pvt. Ltd. |
ZIMDAX | USV LTD. |