Olanzapine with Fluoxetine
Olanzapine with Fluoxetine is a combination medication that contains two active ingredients, olanzapine and fluoxetine. Olanzapine is an atypical antipsychotic, while fluoxetine is a selective serotonin reuptake inhibitor (SSRI). This combination is used to treat certain mental/mood disorders, such as bipolar disorder and treatment-resistant depression.-Bipolar I Disorder: Acute depressive episodes -Major Depressive Disorder: Treatment-resistant depression -Treatment of schizophrenia when adequate response to monotherapy with either agent has not been achieved
Dosage may vary based on the specific condition being treated. It is crucial to follow the prescribing physician's instructions. Typically, initial doses and adjustments are made under close medical supervision.
Olanzapine with Fluoxetine is contraindicated in patients with: -Hypersensitivity to either olanzapine or fluoxetine -Monoamine oxidase inhibitors (MAOIs) or use within 14 days of discontinuing an MAOI
Caution should be exercised in patients with: -History of cardiovascular disease -Diabetes mellitus -Seizure disorders -Suicidal tendencies -Hepatic or renal impairment -Hyperglycemia or diabetes -Hyperlipidemia
Common side effects may include weight gain, somnolence, dizziness, constipation, and dry mouth. Serious side effects may include serotonin syndrome, neuroleptic malignant syndrome, and suicidal thoughts. It is important to promptly report any unusual or severe side effects to a healthcare professional.
Olanzapine with Fluoxetine may interact with other medications, including: -Monoamine oxidase inhibitors (MAOIs) -Serotonergic drugs -Anticoagulants -Antidepressants -Antipsychotics -Drugs that may affect the QT interval -It is crucial to inform the healthcare provider about all medications being taken, including prescription, over-the-counter, and herbal supplements.
