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It is a major metabolite of Phenylbutazone. Its pharmacodynamic, pharmaco-kinetic, toxic and drug interaction profile is similar to Phenylbutazone. It is claimed to be better tolerated i.e. less gastric irritation.


Severe rheumatic disorders.


100-200 mg. 2-3 times daily


Hypersensitivity to Oxyphenbutazone Tablet is a contraindication. In addition, Oxyphenbutazone Tablet should not be used if you have the following conditions: Existing bone marrow depression Gastric or duodenal ulcer Hypersensitivity Renal impairment

Special Precautions

Before using Oxyphenbutazone, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side-effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition. Tell your doctor if your con

Side Effects

Nausea, Skin rash, Stomach upset, Acute toxicity, Gastric irritation, Ulceration, Water and fluid retention in the body parts, Hypersensitivity, Hypothyroid, Bone marrow depression

Drug Interactions

If you use other drugs or over the counter products at the same time, the effects of Oxyphenbutazone Tablet may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions.

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