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PIRACETAM

PIRACETAM

Piracetam is a nootropic agent, i.e. a psychotropic drug which improves directly the efficiency of the higher telencephalic functions of the brain involved in cognitive processes such as those related to learning, memory, thought and consciousness, both in normal and deficient situations, without being sedative of psychostimulant. Piracetam exerts those various activities by different ways of action : it modulates brain neurotransmission, promotes metabolic conditions for neuronal plasticity & improves microcirculation through antispasmodic & haem-orrheological properties, without being a vasodilator.

Indications

Cerebral vascular accidents and cerebral insufficiencies, ischemic or even haemorrhagic acute accidents. Mental retardation in children. Behaviour and psychotic problems in old age.


Dosage

Adults: 800 mg three times a day. Children: 50 mg/kg bodywt in 3 separate doses. Once the desired result has been obtained, reduce the initial dose by half.


Contra-Indications

Hypersensitivity, severe renal impairment,hepatic impairment.


Special Precautions

impaired renal or hepatic functions, cardiac disorders. Paediatrics: Reduce dose according to weight/age. Pregnancy & Lactation: Use with caution. Elderly: No special problem.


Side Effects

Epigastric distress, CNS stimulation, dizziness, excitement, skin rash, sleep disturbances, diarrhoea, depression, weight gain.


Drug Interactions

Inhibits and reverse sickling of RBCs.


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