PIROXICAM-b-CYCLODEXTRIN

This is a complexation entity of piroxicam with b-cyclodextrin. The complexation of PIROXICAM with b-cyclodextrin facilitates the release of piroxicam at the gastric mucosal level in the form of free molecules which can then be absorbed later. This also results in less gastric irritation due to reduced contact time with gastric mucosa. The complexation of PIROXICAM with b-Cyclodextrin is in the ratio of 1:2.5.

Indications

Musculoskeletal pain, pain associated with dysmenorrhoea, headache, post-traumatic pain, post operative pain, migraine, low back pain, rheumatoid arthritis, osteoarthritis, dental pain.

Dosage

1 Tab daily

Contra-Indications

Hypersensitivity, gastric, hepatic, renal disturbances, heart failure, hypertension, severe blood alterations or haemorrhagic diathesis, NSAIDS, pregnancy, lactation and children.

Special Precautions

Before using Piroxicam-Beta-Cyclodextrin / Piroxicam, inform your doctor about your current list of medications, over the counter products, allergies, pre-existing diseases, and current health conditions . Some health conditions may make you more susceptible to the side-effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert.

Side Effects

G.I. disturbances, skin rash, headache, vertigo, asthenia, change in blood chemistry, increase of BUN.

Drug Interactions

If you use other drugs or over the counter products at the same time, the effects of Piroxicam-Beta-Cyclodextrin / Piroxicam may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions.