POLMACOXIB
Polmacoxib is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2 (COX-2). It is used primarily for its anti-inflammatory, analgesic, and antipyretic properties.-Osteoarthritis: Polmacoxib is used to reduce pain and inflammation associated with osteoarthritis. -Rheumatoid arthritis: It may be prescribed to manage symptoms of rheumatoid arthritis. -Acute pain: Polmacoxib can be used for the short-term relief of acute pain conditions.
-The recommended dosage for osteoarthritis and rheumatoid arthritis is typically 2 mg once daily. -For acute pain, the dosage may vary depending on the severity of the pain and the patient's response to the medication. It's essential to follow the prescribing physician's instructions.
-Hypersensitivity to polmacoxib or any of its components. -History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. -Severe hepatic impairment. -Severe renal impairment. -Active gastrointestinal bleeding or peptic ulcer disease. -Severe heart failure or other significant cardiovascular conditions.
-Use with caution in patients with a history of gastrointestinal bleeding or ulceration. -Monitor liver function regularly during long-term therapy. -Caution in patients with renal impairment or those at risk of renal failure. -Monitor cardiovascular status in patients with a history of heart disease. -Not recommended for use in pregnant or breastfeeding women unless clearly needed. -Avoid concomitant use with other NSAIDs or COX-2 inhibitors.
Abdominal pain, diarrhea, dyspepsia, flatulence, peripheral edema, accidental injury, dizziness, pharyngitis, rhinitis, sinusitis, upper respiratory tract infection, rash
Drugs that Interfere with Hemostasis (e.g. warfarin, aspirin, SSRIs/SNRIs), ACE Inhibitors, Angiotensin Receptor Blockers (ARB), or BetaBlockers, NSAIDS, Digoxin, Exacerbation of Asthma Related to Aspirin Sensitivity
