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Polmacoxib is a non-steroidal anti-inflammatory drug (NSAID) that selectively inhibits cyclooxygenase-2 (COX-2). It is used primarily for its anti-inflammatory, analgesic, and antipyretic properties.


-Osteoarthritis: Polmacoxib is used to reduce pain and inflammation associated with osteoarthritis. -Rheumatoid arthritis: It may be prescribed to manage symptoms of rheumatoid arthritis. -Acute pain: Polmacoxib can be used for the short-term relief of acute pain conditions.


-The recommended dosage for osteoarthritis and rheumatoid arthritis is typically 2 mg once daily. -For acute pain, the dosage may vary depending on the severity of the pain and the patient's response to the medication. It's essential to follow the prescribing physician's instructions.


-Hypersensitivity to polmacoxib or any of its components. -History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs. -Severe hepatic impairment. -Severe renal impairment. -Active gastrointestinal bleeding or peptic ulcer disease. -Severe heart failure or other significant cardiovascular conditions.

Special Precautions

-Use with caution in patients with a history of gastrointestinal bleeding or ulceration. -Monitor liver function regularly during long-term therapy. -Caution in patients with renal impairment or those at risk of renal failure. -Monitor cardiovascular status in patients with a history of heart disease. -Not recommended for use in pregnant or breastfeeding women unless clearly needed. -Avoid concomitant use with other NSAIDs or COX-2 inhibitors.

Side Effects

Abdominal pain, diarrhea, dyspepsia, flatulence, peripheral edema, accidental injury, dizziness, pharyngitis, rhinitis, sinusitis, upper respiratory tract infection, rash

Drug Interactions

Drugs that Interfere with Hemostasis (e.g. warfarin, aspirin, SSRIs/SNRIs), ACE Inhibitors, Angiotensin Receptor Blockers (ARB), or BetaBlockers, NSAIDS, Digoxin, Exacerbation of Asthma Related to Aspirin Sensitivity

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