Potassium citrate and Magnesium citrate

The metabolism of absorbed citrate producs an alkaline load which increases urinary pH and raises urinary citrate. It increases urinary potassium and magnesium by approximately the amount contained in the medication.

Indications

It is indicated for prevention of recurrence of urinary stones, Renal tubular acidosis (RTA) with calcium stones, Hypocitraturic calcium oxalate nephrolithiasis of any etiology, Uric acid lithiasis with or without calcium stones. Thiazide induced hypokalemia and hypomagnesemia in hypercalciuric nephrolithiasis. Relief from burning sensation.

Dosage

Three teaspoons (15ml) diluted with one glass of water, after meals/at bedtime or as directed by the physician.

Contra-Indications

Hyperkalemia, Active urinary tract infection, Renal insufficiency because of the danger of soft tissue calcification and incresed risk for the development of hyperkalemia.

Special Precautions

Hyperkaleia, Gastrointestinal lesions, Renal impairment, Pregnancy, Lactation, Paediatric use.

Side Effects

Minor gastrointestinal complaints, such as abdominal discomfort, vomiting, diarrhea, loose bowel movements or nausea, Patients may find intact matrices in feces.

Drug Interactions

Concomitant administration of potassium magnesium citrate and a potassium sparing diuretic (such as triamterene, spironolactone or amiloride) should be avoided, since the simultaneous administration of three agents can produce severe hyperkalemia.