Potassium Clavulanate

Potassium Clavulanate is a beta-lactamase inhibitor used in combination with antibiotics to enhance their effectiveness. It works by preventing bacterial enzymes from breaking down the antibiotics, thereby extending their spectrum of activity against resistant strains.

Indications

-Treatment of infections caused by beta-lactamase-producing bacteria. -Often used in combination with penicillin-type antibiotics to treat respiratory, urinary tract, and skin infections.

Dosage

-The dosage of Potassium Clavulanate varies depending on the specific antibiotic it is combined with and the infection being treated. -Typically administered in tablet or oral suspension form. Common dosages range from 125 mg to 500 mg of Clavulanate in combination with the appropriate amount of the primary antibiotic.

Contra-Indications

-Hypersensitivity to Potassium Clavulanate or any component of the formulation. -Severe liver dysfunction or history of cholestatic jaundice.

Special Precautions

-Use with caution in patients with a history of liver disease. -Monitor liver function regularly during prolonged therapy. -Ensure proper hydration and monitoring for potential allergic reactions.

Side Effects

-Common: Nausea, vomiting, diarrhea, abdominal pain. -Less common: Allergic reactions, liver enzyme abnormalities, rash, headache.

Drug Interactions

-May interact with anticoagulants, potentially increasing bleeding risk. -Concomitant use with certain antibiotics may alter the effectiveness of either drug. -May affect the absorption of other medications.