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PRESERVATIVE BENZYL ALCOHOL

PRESERVATIVE BENZYL ALCOHOL

Benzyl alcohol is a clear, colorless liquid with a mild, pleasant aromatic odor. It is primarily used as a preservative in various pharmaceutical and cosmetic products due to its ability to inhibit microbial growth.

Indications

Benzyl alcohol is indicated for use as a preservative in injectable medications, topical preparations, and cosmetic formulations. It helps maintain the sterility and stability of these products during storage.


Dosage

The dosage of benzyl alcohol varies depending on the specific formulation and concentration used in the product. It is typically present in very small amounts, often less than 2% in pharmaceuticals and cosmetics.


Contra-Indications

Benzyl alcohol is contraindicated in premature infants and neonates due to the risk of toxicity, particularly when used in injectable medications. Individuals with known hypersensitivity to benzyl alcohol should also avoid products containing it.


Special Precautions

Caution should be exercised when using benzyl alcohol in products intended for pediatric populations, as systemic toxicity can occur in young children. Careful monitoring of dosage and cumulative exposure is crucial to prevent adverse effects.


Side Effects

Common side-effects of benzyl alcohol include local irritation or mild allergic reactions at the site of application. In rare cases, systemic toxicity may manifest as metabolic acidosis, which requires immediate medical attention.


Drug Interactions

There are no significant drug interactions reported with benzyl alcohol when used as a preservative in pharmaceuticals or cosmetics. However, interactions could occur with specific medications if benzyl alcohol is used in higher concentrations or in combination with other agents.


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