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PYRIDOXINE (B6)

PYRIDOXINE (B6)

Pyridoxine and pyridoxamine are readily oxidized to pyridoxal whch is then phosphorylated to Pyridoxal phosphate - the coenzyme form. Pyridoxal dependent enzymes are involved in synthesis of non essential amino acids, tryptophan & sulfur containing amino acid metabolism, formation of 5-HT, dopamine, histamine, GABA and amino levulinic acid. Deficiency symptoms: Seborrheic dermatitis, glossitis, growth retardation, mental confusion, lowered seizure threshold or convulsions, peripheral neuritis and anaemia.

Indications

To prevent and treat isoniazid, hydralazine and cycloserine induced neurological disturbances. Mental symptoms in women on oral contraceptives. Pyridoxine responsive anaemia and homocystinurea. Morning sickness and hyperemesis gravidarum. Convulsions in infants and children.Pyridoxine hydrochloride, commonly known as vitamin B6, is a water-soluble vitamin that plays a crucial role in various bodily functions. It is essential for the metabolism of amino acids, the formation of neurotransmitters, and the maintenance of a healthy immune system. Pyridoxine hydrochloride is often used as a dietary supplement to address deficiencies and support overall health. Pyridoxine hydrochloride is indicated for the prevention and treatment of vitamin B6 deficiency. It may also be recommended for specific medical conditions that affect the absorption or utilization of vitamin B6 in the body.


Dosage

The dosage of pyridoxine hydrochloride depends on the individual's age, health status, and the specific reason for supplementation. It is typically taken orally with or without food. Dosage recommendations should be followed as directed by healthcare professionals.


Contra-Indications

Individuals with hypersensitivity to vitamin B6 or any of its components should avoid supplementation.


Special Precautions

High doses of pyridoxine may lead to toxicity symptoms, including neurological issues. It is important to adhere to recommended dosage guidelines. People with certain medical conditions, such as kidney stones or certain types of anemia, should consult with a healthcare professional before starting pyridoxine supplementation.


Side Effects

Common side effects of pyridoxine hydrochloride are rare when taken at recommended doses. However, excessive intake may lead to neurological symptoms, such as numbness, tingling, or difficulty walking.


Drug Interactions

Pyridoxine hydrochloride may interact with certain medications, including: 1. Levodopa (used in the treatment of Parkinson's disease) 2. Antiepileptic medications 3. Some medications for tuberculosis


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