R DNA HUMAN MONOCOMPENT ISOPHANE INSULIN

R DNA Human Monocomponent Isophane Insulin is a synthetic form of insulin used to control high blood sugar in people with diabetes mellitus. It is an intermediate-acting insulin with a slower onset and longer duration of action compared to regular human insulin.

Indications

This insulin is indicated for the management of diabetes mellitus in adults and children who require insulin for the control of hyperglycemia. It is used to improve glycemic control in patients with type 1 diabetes mellitus and type 2 diabetes mellitus.

Dosage

The dosage of R DNA Human Monocomponent Isophane Insulin is individualized based on the patient's metabolic needs, blood glucose monitoring results, and glycemic control goal. It is typically administered subcutaneously once or twice daily. Adjustments in dosage may be required based on changes in physical activity, meals, or other medications.

Contra-Indications

-Hypersensitivity to R DNA Human Monocomponent Isophane Insulin or any of its excipients. -Episodes of hypoglycemia.

Special Precautions

-Monitor blood glucose levels regularly to adjust dosage as needed. -Caution in patients with renal or hepatic impairment as insulin requirements may be reduced. -Adjust dosage during periods of increased physical activity or changes in diet. -Use with caution in patients with visual impairment or dexterity issues, who may have trouble administering the insulin.

Side Effects

-Hypoglycemia (most common) -Injection site reactions (redness, swelling, itching) -Lipodystrophy at the injection site -Weight gain -Edema -Hypokalemia

Drug Interactions

-Beta-blockers may mask the signs of hypoglycemia. -Alcohol can increase or decrease the hypoglycemic effect. -Corticosteroids, diuretics, and oral contraceptives may increase blood glucose levels, requiring insulin dose adjustments. -Monoamine oxidase inhibitors (MAOIs), salicylates, and sulfonamides may enhance the hypoglycemic effect.