Rabeprazole with Domperidone
Rabeprazole with Domperidone is a combination medication that contains two active ingredients - Rabeprazole, a proton pump inhibitor (PPI), and Domperidone, a dopamine receptor antagonist. This combination is designed to provide comprehensive relief for gastrointestinal disorders by reducing gastric acid production and enhancing gastrointestinal motility.-Gastroesophageal Reflux Disease (GERD) -Peptic Ulcers -Dyspepsia -Gastroparesis -Nausea and Vomiting
Dosage may vary based on the specific condition and individual patient response. Generally, a standard dose might include Rabeprazole 20mg once daily and Domperidone 10mg three times a day before meals.
This medication is contraindicated in individuals with a known hypersensitivity to Rabeprazole, Domperidone, or any of the components. It is also contraindicated in patients with a history of cardiac arrhythmias.
Caution should be exercised in patients with hepatic impairment, renal impairment, or those prone to QT interval prolongation. Avoid use in pregnancy and lactation unless the potential benefits outweigh the risks.
-Common side effects may include headache, nausea, and abdominal pain. -Rare but serious side effects may include cardiac arrhythmias and extrapyramidal symptoms.
-Concurrent use with certain antifungal medications (e.g., ketoconazole) may increase Rabeprazole levels. -Domperidone may interact with drugs that prolong the QT interval, such as certain antibiotics and antipsychotics.
