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Rabeprazole with Levosulpride

Rabeprazole with Levosulpride

Rabeprazole with Levosulpiride is a combination medication that consists of two active ingredients: Rabeprazole, a proton pump inhibitor (PPI), and Levosulpiride, a dopamine antagonist. This combination is designed to address gastrointestinal issues by reducing gastric acid secretion and enhancing gastrointestinal motility.

Indications

-Gastroesophageal Reflux Disease (GERD): To manage symptoms such as heartburn and regurgitation. -Peptic Ulcers: Healing and prevention of ulcers in the stomach and duodenum. -Dyspepsia: Relief of symptoms like bloating, discomfort, and early satiety. -Functional Dyspepsia: Especially when associated with delayed gastric emptying. -Gastrointestinal Motility Disorders: To improve gastrointestinal transit in conditions like gastroparesis.


Dosage

The dosage may vary based on the specific condition being treated. It's crucial to follow the prescribed regimen provided by the healthcare professional. Typically, a common dosage may include Rabeprazole 20mg and Levosulpiride 75mg once daily before meals.


Contra-Indications

This combination is contraindicated in individuals with a known hypersensitivity to Rabeprazole, Levosulpiride, or any of the excipients. Patients with severe liver or kidney impairment should also avoid this medication.


Special Precautions

Patients with a history of hypersensitivity reactions should be closely monitored. Caution is advised in elderly patients, and dosage adjustments may be necessary. This combination should be used with caution in pregnant and lactating women. Avoid alcohol consumption during the course of this medication. Patients with neurological disorders or a history of seizures should use this medication cautiously.


Side Effects

Common side effects may include headache, nausea, abdominal pain, and dizziness. Serious side effects such as allergic reactions, irregular heartbeat, or severe gastrointestinal issues should be reported to a healthcare professional immediately.


Drug Interactions

-Warfarin: Potential interaction leading to changes in international normalized ratio (INR). -Digoxin: May increase digoxin levels in the blood. -Ketoconazole: Reduced absorption of ketoconazole when taken concomitantly.


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