Rebamipide Mucogen

Rebamipide is a medication primarily used for its mucoprotective and anti-ulcer properties. Rebamipide is an amino acid analog of quinolinone. It is used for treatment of gastritis and peptic ulcer. It acts by the decrease in oxygen radicals, increase in blood flow and production of protective prostaglandins in ulcer mucosa, which accelerates the process of healing. Rebamipide is a quinolinone derivative that exerts its therapeutic effects by enhancing the production of mucin, a protective substance that forms a barrier on the surface of the stomach and intestines. It also possesses anti-inflammatory and antioxidant properties.

Indications

-Rebamipide is indicated for the treatment of various conditions, including: Gastric ulcers Duodenal ulcers Erosive gastritis Gastroduodenal mucosal lesions associated with nonsteroidal anti-inflammatory drugs (NSAIDs) Helicobacter pylori eradication therapy Treatment of dry eyes -Behcet`s disease, recurrent oral aphthous, ulcers (aphthae), skin lesions, uveitis, and genital ulcers. It`s used as both a treatment, and a prevention.

Dosage

-oral; 100mg three times a day. -The dosage of Rebamipide may vary based on the specific condition being treated. It is typically taken orally, and the recommended dosage should be determined by a healthcare professional.

Contra-Indications

Rebamipide is contraindicated in individuals with known hypersensitivity to the drug.

Special Precautions

-Special precautions should be taken in the following situations: 1. Pregnancy and breastfeeding: The safety of Rebamipide during pregnancy and breastfeeding has not been established, and therefore, its use should be carefully considered in these situations. 2. Renal or hepatic impairment: Adjustments to the dosage may be necessary in patients with impaired renal or hepatic function. Paediatric: Data not sufficient Pregnancy: Category C Lactation: Not to be used Elderly: Data not sufficient

Side Effects

-Common side effects of Rebamipide may include gastrointestinal disturbances, headache, and dizziness. Serious side effects are rare but may include allergic reactions. Patients should seek medical attention if they experience any unusual or severe side effects. -Nausea, Vomiting, Painful abdomen, Upset stomach, Diarrhea, Gastrointestinal tract problems, Generalized myalgia, Increased risk for thrombosis

Drug Interactions

There are limited known drug interactions with Rebamipide. However, it's essential to inform healthcare providers about all medications, including over-the-counter drugs and herbal supplements, being taken concurrently.