S-Adenosylmethionine

S-Adenosylmethionine, commonly known as SAMe, is a naturally occurring compound in the body that plays a crucial role in various biochemical processes. It is synthesized from methionine and adenosine triphosphate (ATP). SAMe is available as a dietary supplement and is involved in the synthesis of neurotransmitters and other important molecules.

Indications

SAMe is often used as a dietary supplement to support mood and emotional well-being. It may also be considered for certain liver disorders and osteoarthritis. Consultation with a healthcare professional is recommended before starting SAMe supplementation.

Dosage

Dosage of SAMe may vary based on the specific health condition. Standard dosages range from 200mg to 1600mg per day, divided into multiple doses. Individual responses to supplementation can differ, and it's essential to follow healthcare provider recommendations.

Contra-Indications

SAMe supplementation is generally well-tolerated. However, individuals with bipolar disorder should exercise caution, as SAMe might affect mood. Pregnant or breastfeeding individuals should consult with their healthcare provider before using SAMe.

Special Precautions

Patients with underlying psychiatric conditions should use SAMe under the guidance of a mental health professional. SAMe may interact with certain medications, so it's crucial to inform the healthcare provider of all prescribed and over-the-counter medications.

Side Effects

SAMe is generally considered safe when used as directed. Common side effects may include nausea, gastrointestinal discomfort, or mild insomnia. Serious side effects are rare but should be reported to a healthcare provider.

Drug Interactions

SAMe may interact with medications such as antidepressants, levodopa, and certain medications metabolized by the liver. Discuss all medications with a healthcare professional to avoid potential interactions.