Diabetes mellitus type 2.
Oral: 2.5-5mg daily irrespective of meals.
Paediatric: Safety cannot be established. Pregnancy: Category B; use if needed. Lactation: Not known if secreted in milk, use with caution. Elderly: Renal function may decrease with age so use with caution.
Upper respiratory infection, headache, abdominal pain, low blood sugar (which is most likely to occur if saxagliptin is taken with other diabetes drugs), Sweating, Shakiness, Extreme hunger, dizziness, cold sweats, loss of coordination, difficulty speaking, confusion, seizures, pancreatitis, An unexplained rash, Itching, Unexplained swelling (especially of the lips, mouth or throat), Wheezing or other breathing problems.
Ketoconazole, strong CYP3A4/5 inhibitors e.g., Atazanavir, Clarithromycin, Indinavir, Itraconazole, Nefazodone, Nelfinavir, Ritonavir, Saquinavir and Telithromycin.