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TERBINAFINE

TERBINAFINE

It is a synthetic antifungal compound and is an allylamine derivative. It acts by inhibition of squalene epoxidase in the fungal cell membrane.

Indications

Fungal infections of the skin caused by dermatophytes like Trichophyton spp., Microsporum spp., Epidermophyton spp. Orally indicated in the treatment of onychomycosis caused by dermatophytes.


Dosage

Adults: 250 mg for a duration of 2-6 weeks in Tinea pedia, 2-4 weeks in Tinea corporis/cruris, 2-4 weeks in Candidiasis, 4 weeks in Tinea capitis, 6-12 weeks in onychomycosis. Children: 2 yrs. and old: upto 20 kg bodyweight and above): 62.5 mg once a day; 20 to 40 kg body weight: 125 mg once a day; > 40 kg bodyweight: 250 mg once a day.


Contra-Indications

Hypersensitivity to terbinafine.


Special Precautions

Pre-existing liver or renal impairment, irregular use or premature discontinuation carries the risk of recurrence of infection. Elderly patients, pregnancy, lactation.


Side Effects

Gastrointestinal symptoms, skin reactions, taste disturbance, hepatobiliary dysfunction, haematological disorders.


Drug Interactions

Negligible potential for inhibiting or inducing the clearance of drugs that are metabolised via cytochrome system e.g. cyclosporin, tolbutamide or oral contraceptives. Drugs that induce or inhibit microsomal enzymes may interfere with terbinafine metabolism. Terbinafine decreases caffeine clearance.


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DERMAPLUS T 250 LEO FORMULATIONS (P) LTD.
DERMAPLUS-T LEO FORMULATIONS (P) LTD.
DERMIN-250 ELEGANCE SKIN CARE
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ENAFIN ENRICO PHARMACEUTICALS
FINTER-250 ALEXIN BIOSCIENCES
FINTERB ANGIA RX DRUG FORMULATION
FLOFINE FLORIS SKIN CARE
FUNGOTEK FDC LTD.
GLOTER GLOBATE PHARMA
HU-TERB HUMAN CARE REMEDIES
ICOTERB 250 ICON LIFECARE PVT. LTD
IFIN GLENMARK PHARMA
KERBINA MARTYN NIKK PHARMA PRIVATE LIMITED
KYREBEST GAENR BIOTEC
LAMISIL NOVARTIS INDIA LTD
LIFINE LIZA LIFE SCIENCE
LIV-ALLEGRA LIVES ON PHARMACEUTICALS
MEGAFIN THRIFT PHARMACEUTICALS PVT. LTD.
MONITER MONICHEM HEALTH CARE PVT. LTD.
MYCOSEAL ORGANIC LAB PVT. LTD.
NAFY-250 SOLARIUM HEALTHCARE
NU-TOR SARAN BIOTECH
SEBIN-250 SPARSHMART PHARMACEUTICALS PVT. LTD.
SKICAN T LEO FORMULATIONS (P) LTD.
STAYBIN HEALTH GUARD (INDIA) PRIVATE LIMITED
T-DERV DARVINCARE
TABBY RADDISON HEALTH CARE PVT. LTD.
TEBATE EFZED DERMA CARE (BEST BIOTECH)
TEBZY SPARK HEALTHCARE PVT.LTD
TERBACT CANBRO HEALTHCARE
Terbeka Regency Healthcare
TERBEKA-250 Regency Healthcare
TERBEST SYSTOPIC LABORATORIES LTD.
TERBETER HEALSURE LIFESCIENCES PVT.LTD
TERBIAMB AMBLE DERMACARE
TERBICA Aryca Pharmaceuticals
TERBICA-250 Aryca Pharmaceuticals
TERBIDEX AXTER PHARMA
TERBIEVE MEDCURE ORGANICS
TERBIEVE MEDCURE ORGANICS
TERBIFLAR SHINY PHARMACEUTICALS P.LTD
TERBIFOR FORTUNE LABS
TERBIHOX HOCHEST BIOTECH
TERBIJOHN JOHNLEE PHARMACEUTICALS PVT LTD
TERBIKING STARGEOMED
TERBIKVER Gelmek Healthcare
TERBIKYOR LIFEKYOR PHARMACEUTICALS
TERBIKYOR LIFEKYOR PHARMACEUTICALS
TERBILIS ELIS PHARMACEUTICALS INDIA PVT. LTD.
TERBIMAC-250 PURPLE INC.
TERBIMITE LOTION AMERICAN REMEDIES
TERBIMITE-250 AMERICAN REMEDIES
TERBINACE SHILAR PHARMACEUTICALS
TERBINE DETROIT INC.
TERBINE DETROIT INC.
TERBINIP-250 Naira Derma (Div. of Dhamus Pharma)
TERBIROM RHOMBUS PHARMA PRIVATE LIMITED
TERBIS IRIS BIOSCIENCES
TERBISA SAYONA
TERBISEV SEVAM (ULTRA HEALTHCARE)
TERBISHINE UNIPATH HEALTHCARE
TERBITEK MEDITEK LIFESCIENCES PVT. LTD.
TERBITIS AROMENTIS LABORATORIES PVT. LTD.
TERBIVIS VISION MEDILINK
TERBIWAY LEZAA BIOTECH
TERBIWIN PIYUSH PHARMA
TERBIWON CYME
TERBIZ Zenoks Biotech Pvt. Ltd.
TERBIZU SOLACIA PHARMA
TERBOGEN SIGNA
TERBOSIL SILICON PHARMA
TERBOTAC SYNOKEM PHARMACEUTICALS LTD.
TERBUNATE SOMSA PHARMACEUTICALS
TERBYZON TAB BLAZON BIOTEK
TERCENA INCEPTA Division Of Aster Medipharm Pvt. Ltd
TEREJM FOREX PHARMACEUTICAL
TERFIDERM NOVAZING PHARMA PVT.LTD
TERFIN WEST-COAST PHARMACEUTICALS WORK LTD
TERFINA DISECURE PHARMA
TERGEM DERMOGEM
TERGEM DERMOGEM
TERICAP TAB CAPITAL PHARMA
TERLITE ABROS (DIVISION OF LUMAIRE LABS PVT. LTD.)
TERMETA PLEASURE BIOTECH
TEROFIN AAN PHARMA PVT LTD
TEROGOOD ADEN HEALTHCARE
TERSOFINE SOVIA ALTIS
TFN SALVO DRUGS PVT. LTD.
TINASURE JUPIVEN PHARMA
TIRGEM DERMOGEM
TORABEST VIVIA DERMA CARE
Tretijon JOHNLEE PHARMACEUTICALS PVT LTD
TRUTERB NEXUS BIOTECH
TURBO ARUNABH PHARMA
TURBODAL DERMACARE (DALLAS)
TURBY OSCODERMA
TURFINE OMNI LIFESCIENCES
TURFINE OMNI LIFESCIENCES
TYZA-DP NICHOLAS PIRAMAL INDIA
XTRA OREVA DERMACARE
ZIMISIL DEWCARE CONCEPT
ZIMISIL DEWCARE CONCEPT
ZINAFIN forman medics pvt. ltd.
ZOTERB PRISM LIFESCIENCES
Zygter Encore Pharmaceuticals Inc
Zygter Encore Pharmaceuticals Inc
ZYTER ZORION DRUGS & HERBS PVT.LTD
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Brand Name Manufactured by
BIFINE-PLUS ARCHICARE
CANOBACT-OZ CANSAS LIFECARE
Cipjohn-NF JOHNLEE PHARMACEUTICALS PVT LTD
COUNT-5 Gelmek Healthcare
CUDERM-T INVOMED COTAB PVT. LTD.
DERMA KT PLUS MARXX PHARMA
DERMA RX NEO MARXX PHARMA
DERMIN RENOWED LIFESCIENCES
DERMIQUAD PLUS MARXX PHARMA
DERMONIA CREAM UNICO DRUGS
DISEDERM DISECURE PHARMA
GLOTER GLOBATE PHARMA
IGCON STAR CREAM LIFECOM PRIMA (INDIA) PVT. LTD.
ITRAFORCE-T MARXX PHARMA
ITRAKUS PLUS INDKUS BIOTECH INDIA
ITRAKYOR PLUS LIFEKYOR PHARMACEUTICALS
ITRAKYOR PLUS LIFEKYOR PHARMACEUTICALS
ITRAMEK-T CREAM Gelmek Healthcare
ITRAMEK-T CREAM Gelmek Healthcare
ITRATEK PLUS MEDITEK LIFESCIENCES PVT. LTD.
ITRATEK T MEDITEK LIFESCIENCES PVT. LTD.
ITRONA T LEO FORMULATIONS (P) LTD.
KONSA-TR FORTE SAYONA
LIV-ALLEGRA-M LIVES ON PHARMACEUTICALS
MICOGENT KAPEETUS MEDICORP
MOMECORT DR. DERMA EXPERT SKIN CARE & CURE
MOMESONE-T INTAS PHARMACEUTICALS LTD.
MOMORG-T MEDCURE ORGANICS
NADOXIN PLUS WOCKHARDT LTD.
O2 MIX PLUS SIGNA
OFAD-CT ADUM HEALTHCARE
OFLODERM LITMUS PHARMA
OFLORIS-TC CARIS LABS
OFLORON-CT RONAK LIFECARE PRIVATE LIMITED
OFLOXICA DERMA Aryca Pharmaceuticals
ORNIFLOX- CT PLUS INDKUS BIOTECH INDIA
PALDERM 5+ PALAS PHARMA
PINKUF-AM PINARC LIFE SCIENCES
PROBETA-T ELEGANCE SKIN CARE
ROSADERM+ SSR BIOTECH
SEFITRA-T SAPHNIX MEDICURE
TERABEST VIVIA DERMA CARE
Terbest Cream SYSTOPIC LABORATORIES LTD.
TERBICLEAR BIOPOLIS LIFESCIENCES
TERBIMOS PLUS HAMSWELL LIFECARE
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TERBIROM-M RHOMBUS PHARMA PRIVATE LIMITED
TERBONIK-OC JAINIK LIFE SCIENCES
TERBOSIL-M SILICON PHARMA
TERBOTAC M SYNOKEM PHARMACEUTICALS LTD.
TERBUNATE-IT SOMSA PHARMACEUTICALS
TERCENA-M INCEPTA Division Of Aster Medipharm Pvt. Ltd
XTAFINE WINTECH PHARMACEUTICALS
ZIMISIL-PLUS DEWCARE CONCEPT
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