Thalidomide
Acute treatment of the cutaneous manifestations of moderate to severe erythema nodosum leprosum (ENL).
Drug prescribing to women of childbearing potential should be contingent upon initial and continued confirmed negative results of pregnancy testing. Multiple Myeloma : Thalidomide is administered in combination with dexamethasone in 28-day treatment cycles.The dose of Thalidomide is 200mg administered orally once daily with water, preferably at bedtime and at least 1-hour after the evening meal. The dose of dexamethasone is 40mg daily administered orally on day 1-4, 9-12, and 17-20 every 28 day
Severe birth defects, primarily phocomelia or death of the fetus, is extremely high during the critical period of pregnancy. Pregnancy, and women capabel of becoming pregnant.
Hypersensitivity and bradycardia.
Drowsiness/somnolence, peripheral neuropathy, dizziness/orthostatic, hypotension, neutro-penia, and HIV viral load increase.
