TIMOLOL MALEATE
It is a beta adrenergic blocking agent. It does not have significant intrinsic sympathomimetic, direct myocardial depressant, or membrane stabilizing activity. Its ophthalmic solution is instilled topically in the eye which reduces elevated as well as normal intraocular pressure. In most studies timolol has been demonstrated to reduce the production of aqueous humour without affecting the visual acuity, size of pupil or accomodation. Thus dim or blurred vision and night blindness produced by miotics are not evident.Chronic open angle glaucoma, aphakic glaucoma, secondary glaucoma. Lowering of intraocular pressure.
1 drop of 0.25% soln. in the affected eye(s) twice daily. If the response is inadequate 0.5% soln. may be used in the same manner.
Hypersensitivity.
Periodic assessment of response. Monitoring of ocular status is advised during prolong therapy. In patients with known contraindications to systemic use of beta-blockers such as bronchospasm, congestive heart failure, heart block. Children, pregnancy or lactation.
Transient burning sensation, blurred vision, mild ocular irritation. Bronchospasm. Reduction in resting heart rate & blood pressure.
