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TOBRAMYCIN

TOBRAMYCIN

It is an aminoglycoside, highly soluble in water & is stable for several weeks in solutions of various pH. Tobramycin is minimally protein-bound suggesting that more of a topically applied drug is available for ocular absoption rather than being bound by tear proteins & inflammatory exudate.

Indications

Treatment of external infections of the eye and its adnexa caused by susceptible strains of gram-positive, gram-negative & other probable resistant bacilli. Safe & effective in children.


Dosage

1-2 drops in the affected eye(s) every 4 hrs.


Contra-Indications

Hypersensitivity.


Special Precautions

Not for injction into the eye. If sensitivity reaction occurs, discontinue. Prolong use. Pregnancy, lactation.


Side Effects

Localised ocular toxicity and hypersensitivity including itching and swelling and conjuctival erythema.


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