TRIFLUPERIDOL

Neuroleptic agent which exerts both a tranquillising & a sedative effect. Though exact mechanism of its action is unknown but evidence suggest that it blocks dopamine receptors within the C.N.S.It is slightly more potent than haloperidol.

Indications

Management of acute & chronic psychoses and anxiety neurosis; antiemetic neuro- leptanalgesia (with narcotic analgesic). Schizophrenia, manic state. Lack of contact. Autism.

Dosage

Initially 0.5 mg daily; increasing by 0.5 mg every 3-4 days to a max. of 8 mg daily.

Contra-Indications

Coma of severe C.N.S. depression. Lesions of the basal ganglia.

Special Precautions

Cardiovascular disorders (may induce hypotension). Not to use C.N.S. depressants concurrently, may produce extra pyramidal symptoms and tardive dyskinesia. Patients with history of convulsive disorders. May induce variations in endocrine secretions. Impaired alertness.

Side Effects

Drowsiness, nausea, blurred vision, hypotension ,tachycardia, dry mouth, jaundice. Extra pyramidal reactions & tardive dyskinesia, skin reactions and photo-sensitivity.