Trimetazidine

It protects the ischaemic cell from the metabolic consequences of ischaemia. It specifically opposes intracellular acidification, reduction in energy production and free radical over production. Trimetazidine prevents the electro physiological manifestations of ischaemia.

Indications

Ischaemic heart disease (angina pectoris, sequelae of infarction)

Dosage

Adults: 20mg thrice daily after meals. Children: Not recommended.

Contra-Indications

Hypersensitivity.

Special Precautions

Paediatrics: Not recommended. Pregnancy: Should not be used. Lactation: Should not be used. Elderly: Caution should be taken.

Side Effects

G.I. disturbances, nausea, vomiting.

Drug Interactions

None reported.