Trospium Chloride

Trospium chloride is an anticholinergic agent with predominantly peripheral nonselective antimuscarinic activity lacking central nervous system effects.

Indications

Overactive bladder

Dosage

Oral; 20mg twice daily, to be take empty stomach

Contra-Indications

Urinary retention; gastric retention, toxic megacolon; uncontrolled narrow-angle glaucoma, Hypersensitivity; myasthenia gravis; tachyarrhythmia; severe renal or hepatic impairment.

Special Precautions

Pregnancy: Category C; Use if risk to fetus outweighs benefits. Elderly : Adjust the dose according to tolerability

Side Effects

Dry mouth, dry eyes, blurred vision, flatulence, constipation, abdominal pain, nausea, vomiting, dyspepsia, urinary retention, tachycardia.

Drug Interactions

Anticholinergic drugs, b sympathomimetics, metoclopromide. it alters GI motility so affect absorption of other drugs.