Vonoprazan
Vonoprazan is a potassium-competitive acid blocker that inhibits H+, K+-ATPase-mediated gastric acid secretion and is used in the treatment of acid-related disorders and as an adjunct to Helicobacter pylori eradication.Treatment of Duodenal Ulcer, Erosive oesophagitis, Gastric Ulcer, Gastric or Duodenal Ulcers Caused by Low-dose Aspirin, Heartburn. Vonoprazan, in combination with amoxicillin and clarithromycin is indicated for the treatment of Helicobacter pylori (H. pylori) infection in adults
Vonoprazan 10 mg or 20 mg given once daily
Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their doctor.
Avoid foods and drinks that can trigger acid production, such as spicy foods, alcohol, caffeine and smoking. Diarrhea may occur while taking this medicine alone or together with antibiotics. Check with your doctor immediately if you have stomach cramps, bloated feeling, watery and severe diarrhea which may also be bloody sometimes, fever, nausea or vomiting, or unusual tiredness or weakness. This medicine may increase your risk of having fractures of the hip, wrist, and spine.
Stomach inflammation, Nausea, Diarrhea, Indigestion, Bloating, High blood pressure, Stomach pain, Urinary tract infection
The metabolism of Vonoprazan can be decreased when combined with Atorvastatin. The serum concentration of Avanafil can be increased when it is combined with Vonoprazan. The metabolism of Axitinib can be decreased when combined with Vonoprazan. The metabolism of Vonoprazan can be decreased when combined with Azelastine.
