Xylometazoline
These are a agonists which on topical application as dilute solution (0.05-0.1%) produce local vasoconstriction. The imidazoline compounds- naphazoline, xylometazoline and oxymetazoline are relatively selective a2 agonists (like clonidine). They have a longer duration of action (12 hrs) than ephedrine. After congestion is claimed to be less than with ephedrine or phenylephrine. May cause initial stinging sensation (specially naphazoline).Nasal congestion.
Instill 2-3 drops into each nostril.
Pregnancy, glaucoma.
Prolong use to be avoided as atrophic rhinitis & anosmia can occur due to persistant vasoconstriction.Hypertensives. C.N.S. depression.
Stinging sensation, sneezing, dryness of mouth & throat, rebound congestion, mild burning.
Brand Name | Manufactured by |
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NOSERIN NASAL SPRAY | Gelmek Healthcare |