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New Study Shows Promise of Implantable Heart Pump for Children Needing Transplants



A recent study suggests that a small, implantable heart pump could offer a lifeline to children awaiting heart transplants, allowing them to wait at home rather than in a hospital setting. The device, known as the Jarvik 2015 ventricular assist device, augments the heart's blood-pumping action, providing crucial support while a suitable donor heart is sought.


In a small-scale early trial, the pump proved successful for seven children, enabling six of them to undergo heart transplants, while the seventh child's heart recovered independently, rendering a transplant unnecessary. The device, slightly larger than an AA battery, can be implanted in children weighing as little as 18 pounds, allowing them to engage in normal activities while awaiting a donor heart.


Lead researcher Dr. Christopher Almond, a professor of pediatric cardiology at Stanford University School of Medicine, emphasized the significance of this advancement, particularly in comparison to existing options such as the Berlin Heart, which is bulkier, heavier, and associated with higher risks. The Jarvik 2015 device offers a safer and more convenient alternative, drawing on decades of experience with similar devices in adults.


Despite the success of the trial, complications were noted, including a blood clot stroke in one child and heart failure in another. However, researchers remain optimistic about the potential of the device, especially considering the approval for an expanded trial funded by the National Institutes of Health.


The expanded trial will involve 22 patients across multiple medical centers in the U.S. and Europe, marking a significant step forward in pediatric cardiac care. Dr. Almond expressed enthusiasm for the future of the research, highlighting the possibility of better options for children with end-stage heart failure.


The study's findings, reported in the Journal of Heart and Lung Transplantation on May 7, offer hope for improving outcomes and quality of life for children in need of heart transplants.



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