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Fish Oil Supplements Linked to Increased Heart Attack and Stroke Risk in Heart-Healthy Individuals, New Study Finds

In a startling discovery, researchers from China have revealed a potential downside to the widely touted benefits of fish oil supplements. According to their study, published in the esteemed journal BMJ Medicine, the use of fish oil supplements may actually heighten the risk of heart attack and stroke among individuals with good cardiovascular health.


The study, drawing from data on a staggering 415,737 individuals in the UK Biobank, sheds light on a previously unforeseen association between fish oil supplementation and cardiovascular risk. While the benefits of these supplements were evident for those with preexisting cardiovascular conditions, they appear to pose a concerning risk for otherwise healthy individuals.

Lead researcher Dr. Adedapo Adeyinka Iluyomade, a preventative cardiologist at the Baptist Health Miami Cardiac & Vascular Institute, expressed the need for a more nuanced approach to recommending fish oil supplements. "These findings indicate that the recommendation of fish oil should be more selective and tailored to individual patient profiles," he emphasized.

The study revealed that individuals without known cardiovascular disease who regularly consumed fish oil supplements faced a 13% higher risk of developing atrial fibrillation and a 5% higher risk of experiencing a stroke compared to those who did not use fish oil. However, for those with preexisting cardiovascular conditions, the supplements offered a protective effect.

Dr. Iluyomade underscored the importance of distinguishing between primary prevention in the general population and targeted use for those with existing heart health issues. "Fish oil may be more beneficial for patients with preexisting cardiovascular conditions rather than for primary prevention in the general population," he stated.

The findings come amidst a backdrop of conflicting research on the benefits of fish oil supplements. While some studies have highlighted their potential in reducing the risk of heart attack and sudden cardiac death, others have shown minimal impact on overall cardiovascular mortality.

Elana Natker, a registered dietitian and director of consumer and health professional communications for the Global Organization for EPA and DHA Omega-3s, urged caution in interpreting the study's findings. "While this study was on a large population, it was observational in nature with potential confounding factors and no consideration of dose," she cautioned.

Nevertheless, the study authors emphasized the need for further research to elucidate the precise mechanisms underlying the association between fish oil supplementation and cardiovascular risk. Dr. Iluyomade echoed this sentiment, stressing the importance of conducting human clinical trials to establish a clearer understanding of the relationship.

As concerns mount over the potential risks associated with fish oil supplements, the medical community faces a conundrum in balancing the perceived benefits with the newfound risks. With further research warranted, the debate surrounding the use of these supplements for cardiovascular health is likely to intensify in the coming years.


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