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Dr Sunil Singla

Alzheimer’s Disease: How to Delay Early Onset of Alzheimer’s Disease

Dr. Sunil Singla, Director & Head of Department, Neurology, SHALBY Sanar International Hospitals, Gurugram explains that Alzheimer's disease is a devastating neurodegenerative disorder affecting millions of people worldwide, causing progressive cognitive decline, memory loss, and changes in behavior and personality. 

It is a brain ailment that gradually impairs thinking and memory abilities, as well as the capacity to perform even the most basic tasks. Symptoms of the late-onset variety typically begin to show in patients in their mid-60s, while early-onset Alzheimer's, though rare, can occur between the ages of 30 and 60.


Symptoms of Alzheimer's Disease

According to Dr. Singla, Alzheimer's is a progressive disease characterized by memory loss, difficulty in planning, decision-making, and problem-solving, along with mood swings, depression, anxiety, and increased irritability. It can lead to difficulties in locating objects, misplacing items, and disorientation. Personality changes may include withdrawal from social activities and apathy, which can affect hobbies and interests.

Causes and Risk Factors

While the exact cause of Alzheimer's disease is not fully understood, several factors have been identified as potential contributors. Advancing age is the greatest known risk factor, with most cases occurring in individuals aged 65 and older. Genetics also play a role, as certain genes, such as APOE ε4, are associated with a higher risk of developing Alzheimer's. Brain changes, including the accumulation of abnormal protein aggregates like beta-amyloid plaques and tau tangles, are characteristic of the disease. Cardiovascular health is another factor, with conditions such as high blood pressure, diabetes, and high cholesterol increasing the risk. Additionally, lifestyle factors such as lack of physical activity, poor diet, smoking, and limited cognitive stimulation are considered potential contributors.

**Treatment:**

Although there is currently no known cure for Alzheimer's, research suggests that certain steps can be taken to delay its early onset and promote brain health. By adopting a healthy lifestyle and making informed choices, individuals can potentially reduce their risk of developing Alzheimer's disease.

Staying mentally active is crucial, as engaging in activities like reading, puzzles, chess, and learning new skills or languages helps keep the brain sharp. Physical activity also benefits brain health by improving blood flow, reducing inflammation, and promoting the growth of new brain cells. Aiming for at least 150 minutes of moderate-intensity aerobic exercise or 75 minutes of vigorous-intensity exercise per week, with activities like walking, swimming, and dancing, is recommended.

A well-balanced diet rich in fruits, vegetables, whole grains, lean proteins, and healthy fats can also support brain health. Omega-3 fatty acids, found in foods like salmon and walnuts, have been linked to a reduced risk of Alzheimer's, while antioxidant-rich foods like berries, leafy greens, and nuts protect brain cells from damage.

Managing stress is another key factor, as chronic stress can contribute to cognitive decline and increase the risk of Alzheimer's. Practicing stress-reduction techniques such as meditation, deep breathing, yoga, or mindfulness can help lower stress levels and support overall brain health.

Getting quality sleep is essential for cognitive function and memory consolidation. Aim for 7-9 hours of quality sleep per night, with a regular sleep schedule, a relaxing bedtime routine, and a comfortable sleep environment.

Staying socially engaged through meaningful relationships and social interactions stimulates cognitive function and may help reduce the risk of Alzheimer's. Managing chronic conditions such as diabetes, high blood pressure, and obesity is also crucial, as these have been linked to an increased risk of Alzheimer's.

Maintaining mental and emotional well-being is vital for brain health. Practices like mindfulness, meditation, and relaxation techniques can help reduce anxiety and depression, both of which contribute to cognitive decline. Engaging in activities that regularly challenge the brain, such as new hobbies, learning a musical instrument, or picking up a new language, can delay cognitive decline.

If there are concerns about cognitive health or a family history of Alzheimer's disease, it is important to seek professional advice. Early detection and intervention can make a significant difference in managing the progression of the disease.

Delaying the early onset of Alzheimer's disease involves adopting a brain-healthy lifestyle.
By staying mentally and physically active, eating a nutritious diet, managing stress, and maintaining social connections, individuals can potentially reduce their risk and promote long-term brain health. These steps not only benefit the brain but also contribute to overall well-being.


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