Inflammatory bowel disease (IBD) in older adults has emerged as a significant global public health challenge, according to a study published in the January 31, 2025, issue of Autoimmunity Reviews. The research highlights the growing prevalence, incidence, and impact of IBD among the elderly, emphasizing the need for targeted public health interventions.

The study, led by Liji Chen from the Second Clinical Medical College of Guangzhou University of Traditional Chinese Medicine, utilized data from the Global Burden of Disease Study to assess the impact of IBD on aging populations between 1990 and 2019. The findings revealed a substantial increase in the number of prevalent cases, new diagnoses, disability-adjusted life years (DALYs), and deaths related to IBD among older adults during this period.

Although the absolute numbers rose, the age-standardized rates for incidence, prevalence, DALYs, and mortality showed a downward trend. Regions such as the Americas, Europe, and countries with high Sociodemographic Index (SDI) values consistently experienced significant disease burdens. Meanwhile, middle SDI countries witnessed the fastest growth in IBD prevalence and incidence, coupled with the steepest declines in DALYs and mortality.

The age group most affected by IBD in terms of prevalence, incidence, and DALYs was adults aged 60 to 64 years. However, mortality rates were highest among those aged 80 to 89 years. Notably, the study found no significant gender differences in IBD burden among older adults.

The authors emphasized the importance of addressing the rising burden of IBD in aging populations. “Public health officials need to recognize the influence of aging populations and other determinants on the burden of IBD among older individuals, crafting tailored interventions to mitigate this burden effectively,” they wrote.

The findings underscore the urgent need for strategies tailored to older adults to manage the increasing global burden of IBD. Enhanced healthcare policies and age-specific interventions could play a crucial role in reducing the disease’s impact on this vulnerable population.