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Acetaminophen, Phenylephrine, Chlorpheniramine Maleate

Acetaminophen, Phenylephrine, Chlorpheniramine Maleate

This medication combines three active ingredients: acetaminophen, phenylephrine, and chlorpheniramine maleate. Acetaminophen is a pain reliever and fever reducer, phenylephrine is a decongestant, and chlorpheniramine maleate is an antihistamine.


This medication is commonly used to relieve symptoms associated with the common cold, flu, allergies, sinusitis, and other upper respiratory tract infections. It helps alleviate fever, headache, nasal congestion, sneezing, runny nose, and itchy/watery eyes.


Dosage may vary depending on age, weight, and individual response. It is crucial to follow the instructions provided by a healthcare professional or those printed on the product label.


This medication is contraindicated in patients with severe hypertension, severe coronary artery disease, narrow-angle glaucoma, urinary retention, severe liver disease, or hypersensitivity to any of its components. It should not be used concurrently with monoamine oxidase inhibitors (MAOIs) or within 14 days of discontinuing such therapy.

Special Precautions

Caution is advised in patients with certain medical conditions such as hypertension, diabetes, hyperthyroidism, prostate enlargement, and liver or kidney disease. Use with caution in pregnant or breastfeeding women and elderly patients. Avoid alcohol consumption while taking this medication.

Side Effects

Common side effects may include drowsiness, dizziness, dry mouth, blurred vision, constipation, and urinary retention. Serious side effects such as allergic reactions, irregular heartbeat, or difficulty urinating should be reported to a healthcare provider immediately.

Drug Interactions

This medication may interact with other drugs such as MAOIs, tricyclic antidepressants, beta-blockers, anticholinergic drugs, and alcohol. Concurrent use with other medications containing acetaminophen should be avoided to prevent overdose.

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