Albendazole
It has the advantage of single doe administration in many cases like ascariasis, hooworm (both species) and enterobiasis. The mechanism of action of albendazole is similarto that of mebendazole.Single or mixed-intestinal worm infestation aused by NEMATODES-Roundworm, Hookworm, Threadworm, strongyloides, whipworm. CESTODES-Tpeworms(Hydatid disease, cysticercosis)
Adults and children above 2 yrs: 400 mg as a single dose. Strongyloidiasis. Taiasis, H. nana infections: 400 mg once daily for 3 consecutive days. Hydatid disease: 400 mg twice daily with meals for 28 days. Thrapy may be repeated after 14 days interval for a total of 3 cycles.
Pregnancy.
Patients with hepatic or renal disease. In woman of child earing age administer within 7 days of start of normal menstruation. Paediatrics: Cntraindicated in children below 1 year of age. Pregnanc: Contraindicated. Lactation: Contraindicated.
G.I. disorders.
Antidiabetic agents potentiates their actin, H2 antagonists increases the plasma concentration of albendazole.