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Amoxycillin with Clavulanic Acid

Amoxycillin with Clavulanic Acid

Amoxycillin with Clavulanic Acid is a medication that combines the antibiotic Amoxycillin with the beta-lactamase inhibitor clavulanic acid. This combination improves amoxicillin's potency by preventing bacterial enzymes (beta-lactamases) from breaking down the antibiotic. As a result, it is extremely successful in the treatment of a wide variety of bacterial illnesses.

Indications

This combination is used to treat bacterial infections of the respiratory system, urinary tract, skin and soft tissue infections, and infections of the ears, nose, and throat. It is particularly beneficial in treating infections caused by bacteria that are resistant to standard antibiotics.


Dosage

Dosage may vary based on the severity of the infection, patient age, and medical history. It is crucial to follow the healthcare provider's instructions. Typically, the dosage is expressed as a ratio of amoxicillin to clavulanic acid (e.g., 500 mg/125 mg or 875 mg/125 mg). The medication is usually taken with food to enhance absorption.


Contra-Indications

Patients who have had severe adverse responses to beta-lactam antibiotics, clavulanic acid, or any of the ingredients in this formulation should avoid using it. It is also not recommended for people who have previously experienced liver dysfunction or cholestatic jaundice as a result of this combination.


Special Precautions

When providing Amoxycillin with Clavulanic Acid to individuals with a history of liver diseases, use caution because it may impair liver function. During pregnancy, this formulation should be used with caution, and the potential advantages should be balanced against the potential hazards. It is also critical to keep an eye on patients for any signs of allergic reactions or serious side effects.


Side Effects

Nausea, diarrhoea, vomiting, abdominal pain, skin rash, and, in some cases, more serious allergic reactions are common side effects of this combo formulation. If any adverse effects persist or worsen, it is best to seek medical attention.


Drug Interactions

Various drugs may interact with Amoxycillin and clavulanic acid. Certain medications' blood levels may be affected, and vice versa. To avoid potential interactions, patients should inform their healthcare provider about all drugs, supplements, and herbal products they are using. Interactions with probenecid, allopurinol, and tetracyclines, among others, are common. To avoid potential drug interactions, healthcare providers can advise patients on correct drug administration.


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