Armodafinil

It is stimulant drug. Armodafinil is the R-enantiomer of modafinil which is a mixture of the R- and S-enantiomers.

Indications

Obstructive sleep apnea/hypoapnea syndrome, narcolepsy, and shift work sleep disorder

Dosage

Oral; 150 or 250 mg every morning or 150mg daily one hour prior to the work shift.

Contra-Indications

known Hypersensitivity to modafinil or armodafinil.

Special Precautions

Paediatric: safety below 17 years not established Pregnancy: Category C; Use if risk to fetus outweighs benefits. Lactation : Excreted in milk; use with caution Elderly : use with caution

Side Effects

Headache, nervousness, insomnia, agitation, confusion, personality disorders, tremor, anxiety; GI disturbances; hypertension, palpitations, techycardia; angioedema; psychosis, depression, mania, abnormal LFTs. Stevens-johnson syndrome, erythema multiforme, Toxic epidermal necrolysis.

Drug Interactions

Cyclosporin, oral contraceptive, warfarin TCAs.