Atazanavir

It is a protease inhibitor used for the treatment of Acquired Immuno-deficiency Syndrom. Unlike Other Protease Inhibitors, Atazanavir has been reported to have minimal effect on lipid levels.

Indications

It is used in combination with other agents for treatment of AIDS. Individuals taking atazanavir as part of their first anti-HIV drug regimen may still be able to take other PIs, even if they develop resistance to atazanavir. It can be given to children over 6 years of age and adults.

Dosage

300mg Atazanavir is taken in combination with Ritonavir once daily. For treatment naive patients 400mg Atazanavir once daily to be taken with food.

Contra-Indications

Hypersensitivity to Atazanavir or any of its components and in patients taking drugs that are highly dependent on CYP3A4 or UGT1A1 for clearance.

Special Precautions

Cardiac conduction abnormalities, rash, hyperbilirubinemia, nephrolithiasis.

Side Effects

Shortness of breath, iII feeling or flu like symptoms, Fever, Muscle or joint aches, Conjuctivitis, Blisters, Mouth Sores, Facial swelling.