Benazepril

Benazepril is an ACE inhibitor with an esterified ethomycarbonyl moiety. It is a highly effective non-sulfhydryl ACE-inhibitor. It is also beneficial in hypertensive patients with concomitant diabetes, congestive heart failure, hyperuricemia, hyperlipidemia or asthma.

Indications

Treatment of hypertension.

Dosage

10-40mg once daily.

Contra-Indications

Hypersensitivity to ACE inhibitors, history of angioedema.

Special Precautions

Renal disease, renal artery stenosis, hyperkalaemia, anaesthesia, prior treatment with a diuretic, concomitant treatment with potassium sparing diuretics or potassium supplements. Pregnancy: Contraindicated. Lactation: Should be recommended only when the potential benefits to the mother outweighs the potential risk to the infant.

Side Effects

Headache, dizziness, fatigue, cough, somnolence, nausea and postural dizziness.

Drug Interactions

Patients on diuretics may experience excessive BP reduction, K-sparing diuretics and K-supplements can increase the risk of hyperkalemia when used with benazepril.